Changes in glycosylated hemoglobin in short- and semi long-term streptozotocin-diabetic mice and rats.

Accepted October 13, 1983 It is well known that glycosylated hemo globin (HbA1) increases in the blood of diabetic patients. However, only few studies have been reported on the changes in the values of HbA1 in mice and rats. The degree of increase in HbA1 levels was not correlated with the severity of hyperglycemia, duration of diabetes, age of the mouse, or body weight in C57BL/KsJ mice (1). In our previous paper, we reported that the HbA1 value increased in parallel with serum glucose level